What do we know about depression? Is there a difference between sadness and depression? Does everyone who is depressed thinks about or attempts suicide? So many questions, but there are answers that can help. 🧠 Causes of Depression Situational triggers: Significant life events such as job loss, the end of a relationship, or major life transitions. Biological factors: Family history or imbalances in neurotransmitters like serotonin, which helps regulate moods and emotions. ⚖